New Research: How Circadian560 Technology Blocks 99.95% of Sleep-Disrupting Light at the Melanopsin Peak - Published Data Inside

By Suraj Dubey | Senior Optometrist, Researcher & Innovator | Founder, Sleepaxa Private Limited
Patent: IN 587746 (Granted) | IN 202521120977 (Pending) | ORCID: 0009-0003-7510-9254

Every night, over 750 million Indians stare at LED screens before sleep. Every night, that screen emits light at 440-470 nm - directly at the melanopsin photopigment in their retina. Every night, their pineal gland receives the signal: "It's daytime. Don't make melatonin."

Harvard researchers measured the damage: 85% melatonin suppression from ordinary room lighting. Not special lights. Not labs. Just a normally lit room.

We published our most comprehensive technical report to date on Zenodo - 25 peer-reviewed references, 5 clinical studies reviewed, and spectrometer-verified data showing what Circadian560 actually does at every wavelength from 280 nm to 780 nm.

The headline number: 0.00% transmission from 280 to 550 nm. Absolute zero.

What Is Melanopsin and Why Does It Matter?

Your retina has approximately 5,000 specialised cells called intrinsically photosensitive retinal ganglion cells (ipRGCs). They contain a photopigment called melanopsin (OPN4) that peaks at 480 nm but remains significantly active all the way to approximately 560 nm.

When melanopsin detects light in this range, it sends a direct signal to your suprachiasmatic nucleus (SCN) - your brain's master clock. The SCN tells your pineal gland: "It's still light outside. Stop making melatonin." Your body doesn't start preparing for sleep.

The critical point most people miss: melanopsin sensitivity doesn't stop at 480 nm. It extends through the green range with decreasing but still significant potency to approximately 560 nm. A lens that only blocks blue (to 480 nm) or light-cyan (to 500 nm) leaves a significant part of the melanopsin activation range completely open.

The Harvard Data: 85% Suppression from Room Lighting

Source: Gooley JJ, et al. (2011). JCEM. 96(3):E463-E472.

Why Melatonin Matters Beyond Sleep

Melatonin is not just a "sleep hormone." Our published research (DOI: 10.5281/zenodo.19596183) documents eight physiological systems affected:

The Circadian560 Spectrometer Data: Absolute Zero from 280 to 550 nm

This is the core of our published research. Every number below is from spectrometer testing - no estimates, no claims without data.

How Circadian560 Compares: Wavelength-by-Wavelength

The difference is clear: generic lenses leave major parts of the melanopsin range unblocked. Circadian560 blocks every single wavelength from 280 to 550 nm at absolute zero, and still blocks 99.95% at the 560 nm boundary.

5 Clinical Studies: Amber Lenses Work for Sleep

The Right Lens for the Right Time of Day

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The Evening Protocol (Evidence-Based)

Step 1: Put on Circadian560 amber glasses 2-3 hours before your intended sleep time.
Step 2: Keep them on during ALL evening screen use. Even brief unfiltered exposure can partially reset melatonin suppression.
Step 3: Dim your room lights to warm-tone settings for maximum protection.
Step 4: Remove when entering your dark sleep environment.
Step 5: Do NOT wear during daytime - your brain needs morning blue light for alertness and circadian entrainment.

India's Sleep Crisis

Frequently Asked Questions

What does 0.00% transmittance mean?
It means absolute zero light passes through at that wavelength. Our spectrometer measures transmittance in steps of 0.01%. At every wavelength from 280 to 550 nm, the reading is 0.00% - no detectable light passes through.

Why is 560 nm the cut-off?
At 560 nm, melanopsin sensitivity drops to approximately 10% of its peak. Above 560 nm, light has negligible circadian impact. Circadian560 is named after this science-defined boundary.

How is this different from generic amber glasses?
Generic amber lenses don't publish spectral data. They may block only to 480-500 nm, leaving the 500-560 nm extended melanopsin range exposed. Circadian560 blocks to 560 nm with verified data.

Should I wear these all day?
No. Amber lenses block the blue light your brain needs during daytime. Wear only 2-3 hours before bed. For daytime screen use, use DayActive 1.0 (yellow tint).

Is this a medical device?
No. Precision-engineered comfort eyewear designed around published circadian science. Not intended to treat, cure, or prevent any medical condition.

Available with prescription?
Yes. CR-39, MR-8, and high-index (1.67, 1.74) with UV400, anti-reflective, and anti-scratch coatings.

Where to buy?
sleepaxa.in/collections/sleep-glasses | Amazon India | 7+ partner cities

Read the Full Published Research

References

1. Gooley JJ, et al. (2011) Room light suppresses melatonin by 85%. JCEM. 96(3):E463-E472.
2. Brainard GC, et al. (2001) Melatonin suppression action spectrum. J Neuroscience. 21(16):6405-6412.
3. Thapan K, et al. (2001) Action spectrum for melatonin suppression. J Physiol. 535(1):261-267.
4. Burkhart K, Phelps JR (2009) Amber lenses improve sleep quality (RCT). Chronobiol Int. 26(8):1602-1612.
5. Shechter A, et al. (2018) Amber lenses improve insomnia (RCT). J Psychiatr Res. 96:196-202.
6. van der Lely S, et al. (2015) Amber lenses block LED alerting in teens. J Adolesc Health. 56(1):113-119.
7. Esaki Y, et al. (2016) Amber lenses advance circadian phase in DSPD. Chronobiol Int. 33(8):1037-1044.
8. Sasseville A, et al. (2006) Orange lenses prevent melatonin suppression. J Pineal Res. 41(1):73-78.
9. Berson DM, et al. (2002) ipRGC discovery. Science. 295:1070-1073.
10. Reiter RJ, et al. (2016) Melatonin as antioxidant. J Pineal Res. 61(3):253-278.
11. IARC Monographs Vol 98 (2010) - Shiftwork and cancer risk.
12. Patent IN 587746 - NeuroCalm FLX+ (10 claims granted).
13. Patent Application IN 202521120977 - Circadian560 (pending).

Suraj Dubey is the Founder & Head of R&D at Sleepaxa Private Limited (sleepaxa.in) - India's first photobiological eyewear company. ORCID: 0009-0003-7510-9254